Because women are at greater risk than men for developing alcohol related problems. Alcohol passes through the digestive tract and is dispersed in the water in the body. The more water available, the more diluted the alcohol. As a rule men weigh more than women, and pound for pound women have less water in their bodies than men. Therefore a woman’s brain and other organs are exposed to more alcohol and to more of the toxic byproducts that result when the body breaks down and eliminates alcohol.
Source; NIAAA