Scientists have found alcohol can increase the risk of cancer by snapping DNA

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Scientists have found alcohol can increase the risk of cancer by snapping DNA

A new study by the Medical Research Council Laboratory of Molecular Biology at Cambridge University in the UK, commissioned by Cancer Research UK, discovered that when the body processes alcohol it producers a chemical called acetaldehyde, which is harmful to DNA.

The researchers found that acetaldehyde snaps the DNA of stem cells – a type of cell that supplies the many different specialised cells our bodies are made of – which can eventually lead to cell mutations.

To analyse the effect acetaldehyde might cause to stem cells’ DNA, the scientists looked at mice cells that didn’t have acetaldehyde dehydrogenases (ALDH) enzymes, which stop acetaldehyde building up by converting it to acetate, which cells use as a source of energy.

They gave the mice diluted ethanol, the purest form of alcohol, and used techniques to see the DNA inside the cells and read its code.

Professor Ketan Patel, who lead the team of researchers, said: “We saw huge amounts of DNA damage in these cells. Bits of DNA were deleted, bits were broken and we even saw parts of chromosomes being moved about and rearranged.

“Our work definitely shows that external factors, like drinking alcohol, can damage DNA in blood stem cells, meaning it could also damage DNA in other types of stem cells.

“While we didn’t look at whether these mice got cancer or not, previous studies have shown that the type of DNA damage we saw in these mice can considerably increase the risk of cancer.”

As a result, Cancer Research UK urged consumers to reduce their alcohol intake. Cancer is linked to seven types of cancer: liver, breast, bowel, upper throat, mouth, oesophageal and larynx.

Diageo put Ila Byrne out front.

28 minutes ago

“Every day I’m inspired by new things I taste, observe or experience so I try to channel that creative energy into my work & workplace,” Ila Byrne, Innovation Director at features in ‘ latest “Women Running the Liquor World.” Full story:

Diageo put Ila Byrne out front.

28 minutes ago

“Every day I’m inspired by new things I taste, observe or experience so I try to channel that creative energy into my work & workplace,” Ila Byrne, Innovation Director at features in ‘ latest “Women Running the Liquor World.” Full story:

Ryanair urging a ban on alcohol sales in airport bars & restaurants..

 

It is pretty rewarding to see that an idea that we raised 6 or 7 years ago and which back then was seen as something rather radical is now seriously considered by countries.
https://www.irishpost.com/…/complete-alcohol-ban-irish-flig…

 

BY: Rachael O’Connor
October 02, 2019

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THE IRISH Aviation Authority has said that a complete ban of alcohol on flights could be considered and is ‘absolutely on the table’.

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Paul Brandon, the IAA’s head of corporate affairs, was speaking on the RTE radio show Morning Ireland when he was asked if the authority was considering a ban on the sale of alcohol on flights.

“It is absolutely on the table,” Mr Brandon said. “But our preference is to focus on the awareness of the risk if they disrupt a flight.”

His comments come amid a new campaign by businesses including Ryanair, Aer Lingus and the Commission for Aviation Regulation, entitled ‘Not On My Flight’, which aims to raise awareness of the undisputed link between alcohol and ‘air rage’ incidents on flights.

He stressed that for now the campaign is focused on educating passengers on the consequences they will face should they become disruptive while flying, and as of now they are are not banning alcohol, but said that in the future they will “see if there is a need for further action”.

According to Mr Brandon, the number of reported air rage incidents on flights across Europe increased by a third between 2017 – 18.

A study published by the European Union Aviation Safety Agency found that a flight is disrupted approximately every three hours within EU airspace.

In May of this year, a flight from Dublin to Malta descended into chaos when as many as 150 drunken passengers began blaring music, dancing in the aisles and shouting at cabin crew.

See More: Aer Lingus, Air Rage, Alcohol Ban, Flight, IAA, Not On My Flight, Ryanair